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Akiyoshi Kakita Selected Research

5-HT1 Serotonin Receptors

12/2020Serotonin/5-HT1A Signaling in the Neurovascular Unit Regulates Endothelial CLDN5 Expression.

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Akiyoshi Kakita Research Topics

Disease

35Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
06/2022 - 06/2003
27Schizophrenia (Dementia Praecox)
09/2022 - 11/2002
24Parkinson Disease (Parkinson's Disease)
06/2022 - 04/2003
22Neurodegenerative Diseases (Neurodegenerative Disease)
06/2022 - 10/2007
22Neoplasms (Cancer)
04/2021 - 06/2004
17Dementia (Dementias)
01/2018 - 10/2007
16Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
06/2022 - 06/2003
15Alzheimer Disease (Alzheimer's Disease)
05/2022 - 07/2006
15Multiple System Atrophy
11/2021 - 04/2003
14Lewy Body Disease (Lewy Body Dementia)
01/2018 - 04/2003
9Tauopathies
11/2022 - 08/2012
9Glioma (Gliomas)
11/2021 - 10/2011
8Synucleinopathies
01/2018 - 08/2010
7Frontotemporal Dementia (Semantic Dementia)
01/2020 - 08/2011
6Epilepsy (Aura)
01/2022 - 12/2011
6Lymphoma (Lymphomas)
06/2020 - 08/2016
5Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
08/2022 - 04/2007
5Seizures (Absence Seizure)
01/2022 - 06/2015
5Proteostasis Deficiencies
01/2020 - 08/2012
4Sarcoma (Soft Tissue Sarcoma)
06/2022 - 12/2013
4Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
05/2022 - 05/2002
4Corticobasal Degeneration
01/2022 - 05/2002
4Focal Cortical Dysplasia
01/2022 - 12/2011
4Gliosis
10/2021 - 11/2012
4TDP-43 Proteinopathies
01/2021 - 03/2011
4Vasculitis (Vasculitides)
03/2020 - 10/2004
4Neuroepithelial Neoplasms (Gliomatosis Cerebri)
05/2019 - 01/2013
4Tuberous Sclerosis (Bourneville's Disease)
01/2018 - 12/2011
4Motor Neuron Disease (Primary Lateral Sclerosis)
01/2014 - 10/2009
4Mental Disorders (Mental Disorder)
11/2006 - 07/2003
3Huntington Disease (Huntington's Disease)
08/2022 - 02/2016
3Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy)
08/2022 - 08/2012
3Demyelinating Diseases (Demyelinating Disease)
01/2021 - 05/2011
3Multiple Sclerosis
01/2021 - 05/2011
3Leukocytosis (Pleocytosis)
01/2020 - 11/2006
3Nervous System Diseases (Neurological Disorders)
01/2020 - 01/2018
3Atrophy
10/2019 - 08/2012
3Glioblastoma (Glioblastoma Multiforme)
03/2019 - 04/2018
3Brain Diseases (Brain Disorder)
03/2019 - 12/2011
2Coinfection
06/2022 - 12/2020
2Body Weight (Weight, Body)
01/2022 - 06/2008
2Parkinsonian Disorders (Parkinsonism)
12/2021 - 01/2017
2Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
11/2021 - 05/2018
2Hydrocephalus (Hydrocephaly)
04/2021 - 01/2003
2Medulloblastoma
04/2021 - 01/2021
2Status Epilepticus (Complex Partial Status Epilepticus)
12/2020 - 01/2020
2Cerebellar Ataxia (Dysmetria)
12/2020 - 11/2014
2Ataxia (Dyssynergia)
10/2020 - 11/2006

Drug/Important Bio-Agent (IBA)

53Proteins (Proteins, Gene)FDA Link
09/2022 - 11/2002
18DNA-Binding Proteins (DNA Binding Protein)IBA
06/2022 - 05/2007
12polyglutamineIBA
08/2022 - 10/2009
12SynucleinsIBA
06/2022 - 10/2011
11DNA (Deoxyribonucleic Acid)IBA
01/2020 - 10/2004
9UbiquitinIBA
12/2020 - 06/2003
8AntibodiesIBA
08/2019 - 04/2003
8alpha-SynucleinIBA
08/2010 - 04/2003
7Amyloid (Amyloid Fibrils)IBA
05/2022 - 08/2012
6Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
11/2021 - 11/2014
5EnzymesIBA
07/2021 - 01/2018
5Messenger RNA (mRNA)IBA
01/2021 - 07/2003
4Epidermal Growth Factor (EGF)IBA
09/2022 - 05/2005
4Protein AggregatesIBA
06/2022 - 10/2012
4Glial Fibrillary Acidic ProteinIBA
12/2021 - 06/2014
4CytokinesIBA
01/2021 - 03/2004
4RNA (Ribonucleic Acid)IBA
01/2021 - 01/2014
4Glutamic Acid (Glutamate)FDA Link
12/2020 - 01/2012
4Biological ProductsIBA
10/2020 - 12/2011
4Dopamine (Intropin)FDA LinkGeneric
01/2018 - 08/2006
4Amyloid beta-PeptidesIBA
10/2017 - 11/2007
43-Iodobenzylguanidine (Iobenguane)IBA
09/2015 - 01/2007
3Neuregulin-1 (Neuregulin 1)IBA
09/2022 - 06/2009
3Sirolimus (Rapamycin)FDA Link
02/2022 - 01/2018
3alpha-hydroxyglutarateIBA
11/2021 - 11/2014
3ImmunosorbentsIBA
07/2021 - 10/2019
3MicroRNAs (MicroRNA)IBA
06/2020 - 12/2014
32,6-dinitrotoluene (DNT)IBA
06/2018 - 01/2013
3GadoliniumIBA
03/2018 - 06/2013
3Carrier Proteins (Binding Protein)IBA
01/2018 - 07/2006
3Aquaporins (Water Channels)IBA
01/2018 - 08/2012
3SteroidsIBA
08/2016 - 10/2004
3Immunoglobulin G (IgG)IBA
11/2014 - 10/2004
3Endopeptidase K (Proteinase K)IBA
10/2011 - 08/2010
2Heat Shock Transcription FactorsIBA
06/2022 - 12/2020
2Superoxide Dismutase-1IBA
06/2022 - 02/2007
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
06/2022 - 05/2010
2Ataxin-3IBA
06/2022 - 10/2020
2FilaminsIBA
05/2022 - 12/2002
2Pharmaceutical PreparationsIBA
12/2021 - 01/2018
2High-Temperature Requirement A Serine Peptidase 1IBA
11/2021 - 05/2018
2tau Proteins (tau Protein)IBA
10/2021 - 01/2020
2LipidsIBA
07/2021 - 10/2015
2Circulating Tumor DNAIBA
04/2021 - 12/2019
2PapainIBA
01/2021 - 05/2011
2CystatinsIBA
01/2021 - 05/2011
2Cysteine Proteinase InhibitorsIBA
01/2021 - 05/2011
2Claudin-5IBA
12/2020 - 11/2017
2Ligases (Synthetase)IBA
12/2020 - 05/2010
2Indicators and Reagents (Reagents)IBA
12/2020 - 05/2011

Therapy/Procedure

9Therapeutics
11/2022 - 10/2004
2Ventriculoperitoneal Shunt
04/2021 - 01/2003